Though Moses and Samuel - Moses had often supplicated for the people; and in consequence they were spared. See Exo 32:11 and following verses, Num 14:13. Samuel also had prayed for the people, and God heard him, 1Sa 7:9; but if these or the most holy men were now to supplicate for this people, he would not spare them.
Cast them out of my sight, and let them go forth - Do not bring them into my presence by your prayers; let them go forth into captivity.