I will punish Bel in Babylon - Bel or Belus was their supreme deity.
That which he hath swallowed up - The sacred vessels of the temple of Jerusalem, which were taken thence by Nebuchadnezzar, and dedicated to him in his temple at Babylon.
The wall of Babylon shall fall - It shall cease to be a defense; and shall moulder away until, in process of time, it shall not be discernible.