Shall it prosper? - Could it be that gratuitous treason should prosper? God will not allow it. “It,” that is, the vine.
he ... pull up - that is, the first eagle, or Nebuchadnezzar.
in all ... leaves of her spring - that is, all its springing (sprouting) leaves.
without great power or many - It shall not need all the forces of Babylon to destroy it; a small division of the army will suffice because God will deliver it into Nebuchadnezzar’s hand (Jer 37:10).