people - the peculiar designation of God’s elect nation (Hos 1:10), that they should be “laden with iniquity” is therefore the more monstrous. Sin is a load (Psa 38:4; Mat 11:28).
seed - another appellation of God’s elect (Gen 12:7; Jer 2:21), designed to be a “holy seed” (Isa 6:13), but, awful to say, “evildoers!”
children - by adoption (Hos 11:1), yet “evildoers”; not only so, but “corrupters” of others (Gen 6:12); the climax. So “nation - people - seed children.”
provoked - literally, “despised,” namely, so as to provoke (Pro 1:30, Pro 1:31).
Holy One of Israel - the peculiar heinousness of their sin, that it was against their God (Amo 3:2).