meaneth not so - He is only thinking of his own schemes, while God is overruling them to His purposes.
think - intend. Sinners’ plans are no less culpable, though they by them unconsciously fulfil God’s designs (Psa 76:10; Mic 4:12). So Joseph’s brethren (Gen 50:20; Pro 16:4). The sinner’s motive, not the result (which depends on God), will be the test in judgment.
heart to destroy ... not a few - Sennacherib’s ambition was not confined to Judea. His plan was also to conquer Egypt and Ethiopia (Isa 20:1-6; Zec 1:15).