feed ... own flesh - a phrase for internal strifes (Isa 9:20).
own blood - a just retribution for their having shed the blood of God’s servants (Rev 16:6).
sweet wine - that is, must, or new wine, the pure juice which flows from the heap of grapes before they are pressed; the ancients could preserve it for a long time, so as to retain its flavor. It was so mild that it required a large quantity to intoxicate; thus the idea here is that very much blood would be shed (Rev 14:10, Rev 14:20).
all flesh shall, etc. - the effect on the world of God’s judgments (Isa 66:15, Isa 66:16, Isa 66:18, Isa 66:19; Rev 15:3, Rev 15:4).