Lit., are for corruption; destined for (εἰς) Corruption, in the physical sense of decomposition.
With the using (τῇ ἀποχρήσει)
Only here in the New Testament. Rather, using up, consumption. Their very using destroys them. Which things-using form a parenthesis.
After the commandments and doctrines (κατὰ τὰ ἐντάλματα καὶ διδασκαλίας)
Connect with Col 2:20, Col 2:21. Ἑντάλματα are specific injunctions. Rev., better, precepts: διδασκαλίας, more general, doctrinal instructions. Both answer to the rudiments of the world (Col 2:20). Compare Matthew 15:1-20; Mark 7:1-23.