And now (kai ta nun). “And as to (accusative of general reference) the now things (the present situation).” Only in the Acts in the N.T. (Act 5:38; Act 17:30; Act 20:32; Act 27:22).
Grant (dos). Second aorist active imperative of didōmi, urgency of the aorist, Do it now.
To speak thy word with all boldness (meta parrēsias pasēs lalein ton logon sou). Literally, “with all boldness to go on speaking (present active infinitive) thy word.” Peter and John had defied the Sanhedrin in Act 4:20, but all the same and all the more they pray for courage in deed to live up to their brave words. A wholesome lesson.