Wherefore (dio). This conjunction applies to the Gentile Christians the arguments in Eph 2:1-10.
That aforetime ye (hoti pote humeis). No verb is expressed, but in Eph 2:12 Paul repeats hoti en tōi kairōi ekeinōi (for pote) “that at that time” and inserts ēte (ye were).
Uncircumcision (akrobustia), circumcision (peritomēs). The abstract words are used to describe Gentiles and Jews as in Gal 5:6; Rom 2:27.
Made by hands (cheiropoiētou). Agreeing with peritomēs. Verbal (Mar 14:58) from cheiropoieō like acheiropoiētos in Col 2:11.