En (in) with locative (ouranōi), epi (upon) with genitive (gēs), hupokatō (under) with ablative (gēs), as in Rev 5:13, including the whole universe, as in Exo 20:4 (Phi 2:10). The MSS. vary in the negative conjunctions after oudeis (no one) between oude - oude (continuative, and not - nor) and oute - oute (disjunctive, neither - nor).
To look thereon (blepein auto). Into the contents of the book. The universe declines the challenge.