Exalted thy voice; by Rab-shakeh, who cried with a loud voice, 2Ki_18:28.
Lifted up thine eyes on high; a gesture of pride and scornfulness, Pro_21:4.
Against the Holy One of Israel: not against man, but against the holy God, who will not suffer thy impious blasphemies to go unpunished; and against the Holy One of Israel, who hath a special relation and kindness to Israel, having as it were set himself apart for them, and set them apart for himself, as being at this time the God of the Jews only, and not the God of the Gentiles; whom, as yet, he suffered to walk in their own evil ways, Act_14:16. And therefore he will plead their cause against thee.