Thou, all the land, or thou, O Jerusalem, or thou, O Zedekiah, the chief of the princes; or else, having spoken of them all in the plural, he now changeth number, and so speaks to each in particular.
Hast despised; hast had very low esteem of them, as if mean and ridiculous.
Mine holy things; all my institutions, temple sacrifices, feasts, and priests, &c.
Profaned my sabbaths; spent them in profane work, or bestowed them upon idols and their service.