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Here are two acts predicated of God, with relation to Paul: the first is a separating of him from the womb; the same was said of two of the great prophets, Isaiah and Jeremiah, Isa_49:1 Jer_1:5. The apostle here is not speaking of God’s decree, predestinating him to eternal life, but of his determining him to the work of an apostle. God predetermineth men to the stations they shall take up in the world; especially such who are to take up stations wherein they are to be eminently useful and serviceable to him. The second act predicated of God is his calling of Paul: this is an act in time, and lieth much in the preparing of persons for the work allotted to them, and in inclining the heart to it. Thus God called Paul, fitting him for the work of the ministry, and inclining him to it; to which he added his immediate command from heaven, that he should go and preach the gospel. Both these acts of God are ascribed to his good pleasure and grace, nothing but his mere free love and favour moving him, either to separate, or to call Paul to this high and great employment.